The Doctor's Dilemma is about Dr. Colenso Ridgeon, who has recently been knighted because of a miraculous new treatment he developed for tuberculosis. As his friends arrive to congratulate him on his success, he is visited by two figures who present him with a difficult decision. He has room for one more patient in his clinic; should he give it to Louis Dubedat, a brilliant but absolutely immoral artist, or Dr. Blenkinsop, a poor and rather ordinary physician who is a truly good person? Dr. Ridgeon's dilemma is heightened when he falls for Jennifer Dubedat, the artist's wife, who is innocent of her husband's profligacy.